There is no effect of having a baby if you are HPV16 positive to negative, you can have a normal pregnancy and delivery. HPV16 is a high-risk type of human papillomavirus, and this virus may cause cervical cancer if it is continuously infected. HPV16 positive to negative, this means that the body is now no longer infected with this virus, it is possible that the virus has been cleared through their own immunity. Since the virus has been cleared, it will no longer cause any adverse effects on the body and will not affect pregnancy and childbirth. For sexually active women, HPV infection should be a relatively common phenomenon, however, the vast majority of women are more resistant, through their own immunity can be cleared of the virus, so that such infections become transient infections, and will not lead to the occurrence of cervical lesions.