Rosuvastatin can be replaced with atorvastatin. Atorvastatin and Rosuvastatin can be applied in patients with normal liver and kidney function in normal times, and the lipid-lowering effect of both is roughly similar, but if the patient has severe renal insufficiency in combination, Rosuvastatin needs to be replaced with atorvastatin, because atorvastatin has almost no effect on kidney function, but patients with normal liver and kidney function can use both Both drugs are fine. It is recommended to control blood lipids within the target range in the process of lipid lowering and lipid reduction, for example, to control LDL cholesterol below 1.4 mmol/L in patients with definite coronary heart disease. In patients with hypertension, diabetes and increased lipids, but no clear manifestation of atherosclerosis such as coronary artery disease is found, try to control LDL cholesterol below 1.8 mmol/L.