Headache patients can take non-steroidal anti-inflammatory drugs, thrombolytic drugs, antiplatelet drugs, lipid-lowering drugs, sedative-hypnotic drugs and antihypertensive drugs, depending on the cause of headache. 1. Headache caused by mental factors and its treatment: headache caused by mental tension and anxiety can be treated by taking diazepam, alprazolam and other sedative-hypnotic drugs or ibuprofen, indomethacin and other non-steroidal anti-inflammatory drugs. 2. Stroke-induced headache and its treatment: thrombolytic drugs such as alteplase, antiplatelet drugs such as aspirin, lipid-lowering drugs such as atorvastatin and painkillers such as loxoprofen can be used for treatment. 3. Headache caused by high blood pressure and its treatment: Headache caused by high blood pressure can be relieved by taking antihypertensive drugs such as valsartan, benadryl and nifedipine. There are many causes of headache, it is recommended that the patient consult a doctor in a timely manner to clarify the cause, under the guidance of the doctor reasonable medication, not blindly self-medication, so as not to cause adverse consequences.