Enteroscopy laxative drink twice is mainly to clean the intestines, and secondly, the laxative will be divided into two times to take, but also can reduce the patient’s sense of pain to take. Enteroscopy is the insertion of the enteroscope from the anus into the intestinal tract, along the intestinal lumen into the ileocecal region, which can directly observe the mucosal lesions of the colon and rectum, such as inflammatory bowel disease, intestinal tumors, intestinal polyps and so on. Colonoscopy requires patients to prepare their intestines in advance and keep them clean in the intestines for the doctor’s observation, so patients need to fast for 6~8 hours before doing colonoscopy and take laxatives to drain the intestinal contents. Clinically used laxatives are mainly polyethylene glycol, lactulose, etc. Different laxatives are taken in different ways, but usually need to drink twice. The main purpose of drinking laxatives twice before colonoscopy is to completely expel the contents of the intestines until watery stools are formed, which facilitates colonoscopic observation. Usually the amount of laxative taken in a single dose is not enough to expel the intestinal contents completely, and there will still be food residues left in the intestines, which is not up to the standard of colonoscopy, so two drinks are needed. If the standard is not met, further doses or enemas may be needed. In addition, the taste of laxatives is more bitter, and the amount of laxatives taken for colonoscopy is relatively large. Taking the laxatives in two separate doses can reduce the pain of taking the medication, and also avoid the irritation of the patient’s intestinal tract caused by taking too many laxatives at one time, which may even lead to vomiting and vomiting out of the medication. Before colonoscopy, patients must strictly follow the doctor’s instructions for intestinal preparation, so as not to affect the results of the examination.