Bone puncture means bone marrow aspiration, which requires percutaneous and transcortical aspiration of bone marrow fluid during the operation and can produce severe pain, so anesthetic must be used. Generally, local infiltrative anesthesia is used, such as procaine but needs to be tested for sensitivity, and lidocaine, which are the two main drugs commonly used for local infiltrative anesthesia. In the local first skin anesthesia, subcutaneous tissue to the periosteum layer by layer anesthesia, that is, the anesthetic to the tissue interstices, so as to produce local infiltration of anesthesia. Even after the use of local anesthesia, when the bone marrow is aspirated, there will be a mild discomfort, aspiration or stinging pain, which is usually very mild, and there will be no pain after the operation. After the anesthetic has worn off, a slight local pain may occur, which usually disappears completely after forty-eight hours.