Pain in the middle of the ribs is also referred to as pain in the middle of the rib cage, and is most commonly associated with inflammation of the rib cartilage or intercostal neuralgia. The most common cause of these two conditions is intercostal neuralgia or inflammation of the intercostal cartilage due to strenuous exercise or accidental sprains from lifting heavy objects, which is mainly characterized by localized pressure and stabbing pain that may radiate from the chest or back. In this case, first of all, we should remove the cause, avoid strenuous exercise, pay attention to rest, local treatment can be applied with hot compresses, you can use hot water bags or hot towels, you can also use topical Fotarine ointment. When the pain is severe, you can also take oral non-steroidal anti-inflammatory and analgesic drugs, such as Xilabao capsules or Nimesulide dispersible tablets. There is also a possibility of herpes zoster, which manifests itself early as a radiating pain along the rib cage and other areas, mainly as a stabbing pain with a more intense level of pain.