Changes in the voice of patients with colds are mainly due to inflammation involving the vocal cords, leading to vocal fold inflammation. Cold is an acute upper respiratory tract infection, mostly caused by viral infection, which can lead to acute inflammation in the upper respiratory tract, including the pharynx and nasal cavity, so it is often easy to involve the vocal cords, resulting in congestion and edema of the vocal cords, which can change the frequency of voice vibration and cause changes in the nature of the voice itself, including frequency, hardness and loudness. Therefore, it is a common symptom for cold patients to have changes in their voice, which can be relieved with glucocorticoid nebulized inhalation therapy, such as budesonide and other drugs.