Coughing at 11, 12 o’clock at night, the reason is more, the most common reason is cough variant asthma or asthma attack early symptoms, need to go to the hospital to check the bronchial diastolic test or bronchial excitation test, can be clearly diagnosed. Asthma is more common in nocturnal episodic cough, you need to chew a chewable tablet of montelukast sodium before going to bed, which can effectively prevent asthma-induced coughing attacks. In addition, daily nebulized inhalation medication is needed for treatment, which involves nebulized inhalation of bronchodilators and glucocorticoids, and the two medications that can be chosen are budesonide and terbutaline. Another cause of coughing at 11:00 p.m. and 12:00 p.m. is most likely due to infection-induced coughing, and at night the bronchial smooth muscle will contract, which will also aggravate the coughing phenomenon, which often requires the use of anti-infective medications and cough and phlegm medications, which can be chosen from the oral solution of aminoglutethimide or the lung force cough combination. Anti-infective drugs can choose Pu Di Lan anti-inflammatory oral solution or blue baicalin oral solution.