Orlistat is suitable for patients with obesity, generally follow the doctor’s instructions to take correctly can achieve the effect of weight loss, but due to individual differences, the effect varies. Orlistat is used for the treatment of obese or overweight patients (body mass index ≥ 24) and is recommended to be taken orally with or within 1 hour after meals. Adverse reactions such as oily spotting, increased gastrointestinal gas evacuation, urgency of stool, steatorrhea, abdominal pain, watery stools, dental discomfort, gingival discomfort, lower respiratory tract infections, headache, menstrual disorders, anxiety, fatigue, and urinary tract infections may occur with the use of this product. If adverse reactions occur, it is recommended to stop the drug and seek medical attention. It is contraindicated for pregnant women, lactating women and those who are allergic to the product. Patients who want to take orlistat for weight loss are advised to go to a regular hospital, consult a professional doctor, cooperate with the doctor to complete the relevant examinations, and avoid blind use of medication.