Multiple bright bands in the lipoma are the description of the ultrasound examination, suggesting that the patient has a lipoma lesion with internal lobular changes, which needs to be followed up and observed in conjunction with clinical symptoms or surgical measures. Lipoma is a common benign lesion, and the cause of its occurrence is related to heredity and abnormal lipid metabolism. In most cases, lipomas occur in superficial tissues, but in a small number of patients, lipomas of organs, such as renal lipomas, may occur. Ultrasound is one of the common methods to examine lipoma, which has the advantages of simple operation, low cost, high detection rate and non-invasive. The description of the presence of multiple strong light bands arranged during the examination suggests the presence of lobulated lipoma in the patient. Due to the presence of an encapsulated structure in the lipoma, it is possible to show an arrangement of multiple strong light bands. Although the disease becomes benign, the lesion may progressively grow in size, resulting in compression symptoms or aesthetic impact. Therefore, depending on the severity of the patient’s clinical symptoms, the patient may be followed up and observed, or the lesion may be surgically removed, and postoperative pathologic examination is routinely required to exclude malignant lesions.