Craniovertebral repair is a relatively common surgical procedure, which is of great significance for repairing cranial defects caused by traumatic brain injuries and craniotomies, in order to restore physiological anatomical repositioning of the skull, to restore effective protection of brain tissues, to restore normal and stable intracranial pressure, and to restore normal circulation of the cerebrospinal fluid, and so on. Therefore, once a cranial defect occurs, cranial bone repair should be carried out in time. However, some patients may not know what department to consult for cranial bone repair. Cranial bone repair should be registered with the Department of Neurosurgery, which is actually a routine procedure in neurosurgery. Although routine, cranial repair is not simple, and its completion is a test of the surgeon’s experience and skill. Because it is a cranial surgery, it must be precise, how to accurately separate the periosteum, deep fascia, and dura mater according to the anatomical structure of various tissues, how to judge and choose the fixation point of the repair plate, and how to cope with intraoperative accidents, such as intracranial hypertension, tissue expansion, etc., which all require the operator to have a deep strength and rich experience. At present, we use a more advanced material called polyether ether ketone PEEK material, which has excellent performance and can overcome the above problems of titanium mesh material, and it has become a new trend of cranial bone repair material.Although the application time of PEEK material is relatively short, a large number of clinical facts have proved that PEEK material has high biocompatibility, fewer complications, can be complex molding, and perfectly fits the defective area, and various properties are very good. During the time PEEK has been used in cranial bone repair, there has not yet been any rejection reaction, and the recovery of patients has been very good, without a single case of complication.