Bitter mouth when swallowing is usually caused by bile reflux due to poor peristaltic function of the patient’s gastrointestinal tract. Under normal circumstances, bile secreted by the liver can be stored in the gallbladder or can enter the duodenum directly through the bile duct to participate in duodenal or small intestinal digestion and emulsify fat so that lipase from the pancreas can break it down into small molecules. In case of poor peristaltic function of the gastrointestinal tract, bile cannot enter the small intestine effectively and may return to the stomach, causing a bitter sensation in the mouth, which is clinically known as bile reflux. Therefore , patients can adjust the food structure, eat a light diet, and consume celery, cabbage, bananas, apples, pears, etc., thus effectively promoting the peristalsis of the gastrointestinal tract and facilitating the digestion and absorption of food. At the same time, patients can also apply power drugs that promote gastrointestinal peristalsis, such as morpholine and cisapride, to reduce the reflux of bile. In addition, patients should adjust their living conditions, take proper rest and actively engage in sports, all of which can promote gastrointestinal peristalsis and avoid bile reflux.