First, there is no history of prolonged heavy alcohol consumption. Second, specific diseases that can lead to fatty liver, such as viral hepatitis, drug-induced liver disease, total parenteral nutrition, and hepatomegaly, are excluded. Third, in addition to the clinical manifestations of the primary disease, there are non-specific symptoms and signs such as malaise, dyspepsia, pain in the liver area, hepatosplenomegaly, etc. Fourth, there may be metabolic syndrome such as overweight or visceral obesity, increased fasting glucose, dyslipidemia, and hypertension. Serum aminotransferase and glutamyl transpeptidase levels may be mildly to moderately elevated, and hepatic imaging manifestations are consistent with the imaging diagnostic criteria for diffuse fatty liver. If more aggressive, a liver biopsy may be performed, and its histologic changes meet the pathologic diagnostic criteria for fatty liver disease.