Statin refers to statins and should not be combined with clarithromycin. Statins can make cholesterol synthesis reduce, so as to achieve the effect of lipid-lowering, mainly used in the treatment of hypercholesterolemia and mixed hyperlipidemia mainly elevated cholesterol. In addition to this, it is also beneficial in preventing the formation of atherosclerosis, in stabilizing and narrowing atherosclerotic plaques, and in preventing and treating coronary heart disease and stroke, and in delaying atherosclerosis. Clarithromycin belongs to the class of macrolide antibiotics, mainly used for respiratory tract infections caused by bacteria, such as tonsillitis, pharyngitis, etc., but its combination with statin drugs will react, making statin drugs increase blood concentration, and even symptoms such as rhabdomyolysis, and thus can not be combined together. It is important to note that people who are allergic to the drug can not use it, pregnant and lactating women, severe liver and renal insufficiency, cardiac arrhythmia, caution with clarithromycin, the use of medication should follow the doctor’s instructions, under the guidance of the doctor, do not take the drug on their own.