Dapoxetine Hydrochloride is one of the most widely used medications for the treatment of premature ejaculation in clinical practice, and it is also the only medication approved specifically for the treatment of premature ejaculation, which chemically belongs to the 5-hydroxytryptamine reuptake inhibitor. Dapoxetine hydrochloride has a better therapeutic effect on both primary premature ejaculation, secondary premature ejaculation, situational premature ejaculation, as well as premature ejaculation-like ejaculatory dysfunction, and can significantly prolong the ejaculatory latency. The use of this drug is rather specific and may not work if not used correctly. Because the drug is absorbed more quickly and has a faster onset of action, sexual intercourse usually takes place one hour after oral intake to achieve good results.