Gastrointestinal mesenchymal stromal tumors are tumors of mesenchymal origin in the gastrointestinal tract. The five-year survival rate of gastrointestinal mesenchymal stromal tumors means the chance of survival of patients with gastrointestinal mesenchymal stromal tumors after five years of surgical treatment, and the “five-year survival rate” is often used in clinics to roughly assess the survival of patients with tumors. In general, the five-year survival rate of gastrointestinal mesenchymal tumors after surgery is about 50% to 65%. However, the specific survival time after surgery varies from person to person and needs to be judged according to the actual situation. It cannot be generalized and is mainly related to the treatment method, physical condition, clinical stage, pathological type and other factors. Since there is a certain recurrence rate of this disease after surgery, so patients need to review the examination on time and regularly monitor the changes of the disease. In summary, patients with gastrointestinal mesenchymal stromal tumor need to actively cooperate with doctors for treatment, strengthen daily life management after surgery, and follow up regularly.