High risk of folate utilization capacity means that the body’s ability to utilize folic acid is relatively low and is the result of a genetic defect in the body. High risk folate utilization is a genetic test performed by the body to screen for low utilization of folic acid, which makes the body susceptible to chromosomal abnormalities such as homocysteinemia. Women who are at high risk for folic acid utilization during pregnancy or in the first trimester of pregnancy are prone to fetal neurovascular malformations and therefore need to take larger quantities of folic acid supplements than the general population. If you are screened for high risk of folic acid utilization, you can take folic acid supplements according to your doctor’s instruction, and you can usually recover after a period of supplementation; if you have any discomfort, please consult a doctor in time and take active treatment, so as to avoid any delay in your condition.