Positive tuberculosis is able to determine whether one is infected by the new coronavirus through the new coronavirus nucleic acid test, the nucleic acid test results are not affected by tuberculosis disease, and it is recommended that the new coronavirus nucleic acid test be performed in a timely manner. Nucleic acid testing refers to the detection of the presence of genetic material of the new coronavirus in the body by quantitative PCR. Nucleic acid testing looks for the presence of nucleic acid of the foreign invading virus in the patient’s respiratory specimen, blood or feces to determine whether he/she is infected by the new coronavirus. Therefore, a “positive” nucleic acid test indicates that the virus may be present in the patient’s body. A positive TB test does not affect the results of the novel coronavirus nucleic acid test. Mycobacterium tuberculosis and the novel coronavirus have different genetic material, and they do not interfere with each other’s results. Tuberculosis positive can do nucleic acid test, tuberculosis positive will not affect the accuracy of nucleic acid test, it is recommended to follow the arrangement of nucleic acid test in a timely manner. Tip: “New coronavirus pneumonia and new coronavirus pneumonia” mentioned in this article were renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.