Clinically, there is no first choice of anti-hepatitis fibrosis drugs, according to their own conditions, follow the doctor’s instructions to use anti-virus, liver protection and anti-fibrosis drug treatment. 1. Antiviral drugs: for patients with fibrosis caused by hepatitis B virus infection, entecavir, tenofovir and other drugs can be used for treatment under the guidance of doctors. For the hepatitis C virus infection, the use of sofosbuvir, dalatasvir and other drugs for antiviral treatment as prescribed by the doctor. 2. Hepatoprotective drugs: such as diammonium glycyrrhizinate and polyene phosphatidylcholine capsules can effectively inhibit the inflammatory response of the liver. 3. Anti-fibrotic drugs: patients can take oral anti-fibrotic drugs under doctor’s advice, such as colchicine, silymarin and so on, which can effectively anti-fibrotic. Once liver fibrosis occurs, patients need to go to the hospital in time. Taking drugs should be applied under the guidance of a doctor to avoid the risk of medication.