Retinoic acid creams can get rid of blemishes, but they are generally only used for epidermal spots such as sun spots and freckles. Retinoic acid cream is a retinoid, which can dissolve skin keratin and regulate the mitosis of epidermal cells. For epidermal pigmented diseases, retinoic acid cream can promote the shedding of diseased epidermis, so it can be used for the treatment of sun spots, freckles and other pigmented diseases. However, for dermal spots such as melasma, retinoic acid cream is less effective. In addition to pigmented skin diseases, retinoic acid cream can also be used to treat acne, ichthyosis, flat warts and other skin diseases caused by abnormal skin keratinization. Retinoic acid cream has a certain degree of skin irritation, some patients will have localized redness, swelling and pain and other symptoms after use, after stopping the medication can usually subside on its own. Vinpocetine cream is generally not recommended for pregnant and breastfeeding women and children. Vinpocetine cream should be used under medical supervision, do not self-medicate.