Hiccups may be caused by external factors, digestive system diseases, central system diseases, peripheral factors and other reasons. 1. External factors: Usually, external factors such as improper diet, mental stress, local cold and other external factors are the causes of physiological hiccups, but by eliminating the unfavorable factors, these undesirable symptoms can generally be relieved and improved. 2. Digestive system diseases: such as gastrointestinal neurosis, Helicobacter pylori infection, etc., there may be gastrointestinal and other digestive tract tissues of the obstruction of the emptying function, a large number of gases and substances in the gastrointestinal lumen formation of stagnation, the esophageal diaphragm will be subjected to the influence of the increased internal pressure, resulting in the occurrence of such uncomfortable symptoms. 3. Central system diseases: usually when patients suffer from alcoholism, uremia, brain tumors and other central system diseases, resulting in the loss of the central reflex arc function, the phenomenon of hiccups may occur. 4. Peripheral factors: usually when patients suffer from gastric cancer, gastric dilatation, esophagitis and other diseases caused by peripheral factors, the reflex arc of the patients is stimulated, which may lead to the phenomenon of hiccups. There may be other reasons for hiccups, so it is recommended that patients actively seek medical treatment to clarify the cause of hiccups and then carry out standardized treatment.