For patients with yellowing of the skin and sclera, first of all, patients need to take blood to check the liver function, blood routine and coagulation function, to see whether the total bilirubin, direct bilirubin and indirect bilirubin in the liver function of the patient are elevated. If the total bilirubin of the patient is above 34.2 μmol/L, yellowing of the skin and sclera can be detected with the naked eye. If the direct bilirubin is mainly elevated, combined with the elevation of alkaline phosphatase and GGT, then the patient needs to further investigate the ultrasound of the upper abdomen and MRCP water imaging of the biliary tract to see what causes obstructive jaundice, whether it is caused by stones in the bile ducts or bile ducts compressed by neoplastic diseases. If the patient is diagnosed with a stone, ERCP lithotripsy should be performed. If it is a tumor, according to the location and size of the tumor, surgery should be considered if necessary. Another situation is that the patient mainly has elevated indirect bilirubin, which is mostly considered to be caused by hepatocellular necrosis. At this time, the patient needs to further examine the blood to see if there is viral hepatitis, if there is viral hepatitis, it is necessary to actively protect the liver treatment, and if the virus suggests that there is replication, it is necessary to actively carry out antiviral treatment.