The difficulty in treating herpes zoster pain and postherpetic neuralgia is mainly related to its pathogenesis. Firstly, the disease is caused by persistent multiplication of varicella-zoster virus infection after nerve latency, and antiviral drugs are not effective; secondly, the virus invasion of nerves can cause structural damage to nerve fibers. Herpes zoster neuralgia is closely related to the patient’s age, with 50% of patients over 60 years of age and 75% of patients over 70 years of age having residual neuralgia. Therefore, the incidence of postherpetic neuralgia is very high in elderly patients. There are still many people who believe that pain medicine is only for chronic pain, so they rarely visit pain medicine during the acute phase, so most patients spend the acute phase of shingles in dermatology, and as a result, they miss valuable time to prevent chronic pain. Early pain management can be very effective in preventing the onset of this intractable pain. It is the most correct treatment and shortens the course of shingles. It has very good social and economic benefits. Patients with shingles are advised to consult the pain department first and also propose the help of fellow dermatologists.