You should not have sexual intercourse while using interferon suppositories, because the suppositories will melt after being inserted into the vagina, and some of them will be absorbed and some of them will be expelled from the vagina. If you have sex at this time, you may introduce bacteria into the vagina during sex, which may aggravate the original condition or cause an inflammatory reaction in the vaginal mucosa. Ejaculation inside the vagina will cause most of the melted interferon to flow out of the vagina along with the semen, which will reduce the effectiveness of the medication, so intercourse is not allowed during interferon use. The actual fact is that you will not be able to get a good deal on your own.