Swollen eyes in the morning, the first thing to rule out is staying up late at night, drinking too much water at night, and after these factors are ruled out, the first thing to do is to be wary of is caused by kidney disease. The most common is acute or chronic nephritis and nephrotic syndrome, chronic renal insufficiency these diseases, especially chronic nephritis, the typical manifestation is lower limb edema and morning eyelid swelling, can be clearly diagnosed by checking the urine routine, creatinine, urea these indicators, the emergence of urinary protein latent blood positive or creatinine, urea increased, suggesting that there is kidney injury. At this time, we need to further check the 24-hour urine protein quantification, as well as renal puncture to clarify the specific type of renal pathology, targeted medication to avoid further kidney damage. In addition to kidney injury can cause eyelid edema, there are other causes, such as eyelid conjunctivitis or hypothyroidism, Cushing’s syndrome and other endocrine diseases, can also cause eyelid edema, which need to be diagnosed by different clinical symptoms and laboratory tests.