Bile reflux taking ursodeoxycholic acid usually 10-14 days to see the effect, the specific time to take depends on the patient’s condition. Ursodeoxycholic acid is mainly used for the treatment of steroidal gallstones, bile reflux gastritis, cholestasis caused by liver disease. If used for bile reflux gastritis, generally 10-14 days to see the effect, the specific time to take according to the patient’s condition; and for the treatment of cholesterol stones generally have a significant effect in 6 to 24 months, the specific time varies from person to person. The drug also has certain side effects, there may be constipation, allergies, headache, dizziness, tachycardia and other discomforts; and for the biliary tract is completely obstructed, severe hepatic hypothyroidism is prohibited; long-term use of the drug process, we need to pay attention to the monitoring of the number of peripheral platelets and liver function, and for pregnant women, breastfeeding women and other special populations, need to be guided by a doctor to use the drug. The above medication should be used under the guidance of a doctor, avoid self-medication to avoid adverse consequences.