The statement that there are 8 early features of hemorrhagic fever is unscientific. There are two main clinical syndromes that occur after human infection with hantaviruses: hemorrhagic fever with renal syndrome (HFRS) caused by hantaviruses Hantaan, Seoul, Pumara, and Dobrava viruses, and hantavirus cardiopulmonary syndrome (HCPS). Typical HFRS has several prominent manifestations: fever, hemorrhage, hypotension, and acute kidney injury (AKI). Puumala virus infection usually presents with high fever, low back or abdominal pain, nausea and vomiting, malaise, conjunctival hemorrhage, headache, and acute myopia with headache. The manifestations of HFRS due to Asian hantavirus infection are more severe. In addition to the manifestations of Puumala virus infection, more than 1/3 of patients have hypotension; oliguria occurs in nearly 2/3 of patients, many of whom may require dialysis; laboratory abnormalities are more severe; and disseminated intravascular coagulation (DIC) may be observed. In Asian patients with HFRS, hantavirus-induced disease is more severe than hantavirus-induced disease, and there is a higher likelihood of shock and dialysis-requiring renal failure. When patients experience these symptoms, they should seek medical attention, and when using medications, it is recommended that they do so under the supervision of a physician.