For patients with intermural fibroids and subplasma fibroids, it is possible to take saffron in moderation because saffron itself has the effect of activating blood circulation and removing blood stasis, which can inhibit the growth rate of fibroids to a certain extent. However, saffron is not recommended for patients with submucosal fibroids, because submucosal fibroids grow towards the uterine cavity and the area of the endometrium is relatively larger. Since the fibroids are under the mucosa of the uterus, the contraction of the uterus may be affected, which may lead to clinically shortened menstrual cycle, prolonged menstrual period, excessive menstrual flow, or even irregular vaginal bleeding. If saffron is then taken, it will aggravate the local bleeding and make the menstrual flow more heavy, which will cause the patient to be anemic, so saffron is not recommended for submucosal uterine fibroids.