After the occurrence of sacral metastasis of bowel cancer, it can be treated by radiotherapy, chemotherapy, targeted drugs and other methods, and the following drugs should be applied under the guidance of doctors. Bowel cancer is a malignant tumor of intestinal tract caused by heredity, gene mutation and other factors. When the disease develops to the advanced stage, bone metastasis can appear, such as sacral metastasis, at this time, there are symptoms such as localized lumps and pain. For advanced bowel cancer, non-surgical therapies are often adopted, such as radiotherapy, i.e. using the energy released by high-energy rays to kill tumor cells; and using blood to make chemotherapeutic drugs, such as 5-fluorouracil and cisplatin, to reach the lesions; and adopting more accurate targeted therapy with less side effects, and the commonly used drugs are bevacizumab, ramorubicin and so on. Specific intestinal cancer sacral metastasis, according to the patient’s condition, professional doctors will evaluate and formulate a reasonable treatment plan, need to actively cooperate with the treatment, keep optimistic mentality, improve the quality of survival and prolong the life span.