Elevated blood pressure in the middle of the night is relatively common in the clinic, mainly seen in the following cases: first, the patient’s blood pressure circadian rhythm pattern is abnormal. The most common is the antipattern blood pressure, for most people tend to be high blood pressure during the day, low blood pressure at night, but the elderly or hypertensive patients, without standardized treatment, blood pressure is prone to this abnormal change, manifested as elevated in the middle of the night; second, sleep apnea, hypoventilation syndrome patients, due to apnea during sleep at night, the formation of hypoxemia will also reflexively cause the blood pressure to rise; third, long-term poor sleep patients, especially hypertensive patients with chronic poor sleep, especially hypertensive patients with chronic hypoxia, will also reflexively cause blood pressure Third, long-term poor sleep patients, especially hypertensive patients with long-term poor sleep, is also prone to blood pressure is not easy to fall, especially in the middle of the night poor sleep coupled with anxiety, it is more likely to appear elevated blood pressure.