Patients with allergic conjunctivitis have the possibility of exacerbating the condition after a good night’s sleep if it is not treated according to specifications. Allergic conjunctivitis occurs when the conjunctival tissues of the patient’s eyes come into contact with allergens in the external environment triggering an allergic reaction. If the patient is untreated, there is a possibility of aggravation of the condition after sleeping because the patient may be allergic to cotton wool, skin debris, mites, etc. attached to bedding, and contact with the above mentioned allergens while sleeping will aggravate the allergic reaction. For treatment, patients should pay attention to changing and washing bedding frequently, and can use anti-allergy eye drops under the guidance of doctors, such as ketotifen fumarate eye drops, olopatadine hydrochloride eye drops and so on. It is recommended that patients with allergic conjunctivitis consult a doctor in a timely manner to assess their condition and follow the doctor’s instructions for treatment.