Acne closure, which is a type of closed acne, is a type of acne rash that can be treated by general treatment, topical medication, systemic medication and other measures. 1. General treatment: keep the skin clean and hygienic, use water or suitable cleansing products to remove excess oil on the skin surface, but avoid excessive washing, pay attention to oil control and moisturizing, avoid scratching and squeezing, eat a light diet to control the glycemic index of food, as well as milk intake, to maintain a smooth bowel movement. 2. Topical medication: Vitamin A acid cream, benzoyl peroxide gel, adapalene gel and other medications can be used externally; antibiotic drugs can be used externally fusidic acid cream, erythromycin ointment. 3. Systemic drug therapy: acne combined with inflammatory papules, papules and other rashes, antibiotic drugs can choose minocycline, doxycycline; Vitamin A acid drugs; anti-androgen drugs, such as birth control pills and spironolactone. Acne occlusion, it is recommended to go to the regular hospital in a timely manner, the above drugs must be used under the guidance of a doctor.