The two drugs, Yi Yao Wan and Zhi Bai Di Huang Wan, when taken together, are effective in tonifying the spleen and kidneys, relieving depression in the liver, and benefiting Qi and blood. Both drugs are more suitable for women to treat symptoms such as night sweats and irritability in menopausal women. It can be used to treat symptoms such as weakness and pale complexion caused by liver depression, spleen deficiency and blood weakness. Zhi Bai Di Huang Wan is composed of Zhi Mu, Shu Di Huang, Huang Bai, Cornu Cervi Pantotrichum, Shan Yao, Mudan Pi, Fu Ling and Ze Xie, etc. It has the effect of nourishing Yin and clearing heat. It is used to treat symptoms such as heart trouble, insomnia and sleeplessness, as well as heat in the five hearts due to deficiency of kidney yin and inflammation of deficiency fire.