Sudden onset of limb weakness in elderly patients requires exclusion of acute cardiovascular and cerebrovascular diseases in most cases. In sudden attacks of coronary heart disease, cerebral infarction, or cerebral hemorrhage, patients may have severe clinical manifestations such as weakness of limbs, headache, nausea, vomiting, and even with loss of consciousness. When such cases occur, a joint examination by relevant departments of cardiology and neurology is required to rule out the presence of stroke and coronary artery blockage related diseases. In addition, endocrine disorders such as hypothyroidism and hypoglycemia may also cause weakness in the extremities of elderly patients, and these patients should be examined for thyroid function, blood glucose and electrolytes. For patients with severe cervical spondylosis in the past, sudden weakness of the limbs may be caused by trauma.