Common causes of increased appetite during chemotherapy include the application of hormones during chemotherapy, which promotes an increased appetite or a reduction in the size of the lesion and remission of the disease. Hormones are often used in combination during chemotherapy to improve the tolerability of chemotherapy, and hormones have the potential to improve appetite. Therefore, patients who have mild gastrointestinal adverse reactions to chemotherapy drugs often have a better appetite if hormones are used in combination. Chemotherapy will make the lesion shrink, especially for patients with high sensitivity to chemotherapy, after the lesion shrinks, it will reduce the pressure effect of the lesion, improve the gastrointestinal function, and appear to have an increased appetite. Therefore, increased appetite during chemotherapy is often a better clinical manifestation, but it is also important to maintain good eating habits and healthy diet according to the patient’s condition.