The efficacy of bile reflux gastritis treatment is related to the treatment measures and not closely related to the way the medication is administered; simple gastritis with bile reflux does not require infusion therapy. Some medications are not available in intravenous form, so oral medication is sufficient for simple bile reflux gastritis. Pharmacological measures for bile reflux gastritis include the use of gastrointestinal dynamics drugs such as domperidone to promote gastric emptying, gastric mucous membrane protective drugs such as bismuth potassium citrate and aluminum thiosulfate to protect the gastric mucous membrane, and antacids such as omeprazole to alleviate the stimulation of gastric acid, and so on. Among the above drugs, gastric mucosal protective drugs such as bismuth potassium citrate and aluminum sulfate are oral drugs. Different routes of administration may differ only in the time of onset of action; other effects are basically the same. When using the intravenous route of administration, if fever, allergy, phlebitis and other infusion reactions occur, it should be stopped immediately. The above drugs need to be used under the guidance of clinicians and unauthorized use is prohibited. When bile reflux gastritis occurs, it is recommended to go to the hospital in time for standardized diagnosis and treatment.