The majority of vaginal blisters are caused by herpes simplex virus infection, which is mainly caused by a decrease in the body’s resistance and immunity to the virus. In the clinical often manifests as vaginal blisters, and localized pain, accompanied by increased vaginal discharge, vulvar itching and other clinical symptoms. It is recommended to use the local cleansing lotion, skin cleansing lotion, or red core lotion to clean the local area, and then apply acyclovir ointment locally for treatment. Wear loose cotton underwear during treatment to avoid friction, which may cause the blisters to rupture and aggravate the local pain. It is recommended to apply acyclovir ointment 3-4 times a day, which can effectively inhibit the further progress of the disease, and make the blisters appear to shrink. Strengthen the nutrition and increase the resistance in order to heal as soon as possible. Do not have sex during the treatment period.