The reasons for getting up in the morning with stomach pain may be the following: First, caused by cold, the patient sleeps at night without covering the quilt, so that the abdomen gets cold and causes stomach pain in the morning. Second, it may be stomach or duodenal disease, the morning up fasting stomach pain, consider the possibility of duodenal-related diseases, such as duodenal ulcer, or the previous day’s diet unclean, resulting in acute gastroenteritis, the morning after the onset and cause stomach pain. Third, stomach pain may also be liver and gallbladder diseases, such as hepatitis, gallstones, etc. Four, stomach pain may also be pancreatitis, pancreatitis is usually seen after drinking or overeating. Fifth, appendicitis, appendicitis is often a metastatic abdominal pain. Six, stomach pain also can not exclude the possibility of heart disease, especially ischemic heart disease, mostly seen in middle-aged and elderly patients, common pain under the saber. Seven, if the stomach pain is female, it cannot be ruled out because of gynecological conditions such as menstruation, pregnancy or ovarian cyst tip torsion. In conclusion, there are many diseases that cause stomach pain and require specific analysis on a case-by-case basis.