Urine protein has (+), a condition that suggests a kidney-related injury. The most common causes are glomerulonephritis, IgA nephropathy, etc. It is recommended to check the 24h urine protein quantification to further evaluate the protein leakage, and then measure the blood pressure to see if there is any hypertension problem. For those with 24h urine protein quantification <1g, we can apply ACEI or ARB drugs to protect the kidney and reduce urine protein. For urine protein quantification >1g, it is recommended to check renal puncture to further clarify the kidney pathology, so as to select a targeted treatment plan. If the protein quantification is large, it is often necessary to add hormones or immunosuppressive drugs to prevent further deterioration of kidney disease.