Blackheads on the nose cannot be removed with toothpaste. This is because blackheads on the nose are actually blackhead pimples, which are mainly due to the sebum secreted by the sebaceous glands on the nose, some of which are not completely discharged from the surface of the skin and so form black pitting due to oxidization on the surface of the skin they are in contact with. This condition, if removed, must be applied topically with either a sebum-removing drug or a drug that relieves skin keratinization. Topical application of adapalene gel or salicylic acid ointment etc. is usually possible. However, toothpaste does not have this effect, and the main ingredient of toothpaste is a cleansing ingredient, which at best can make the nose appear clean, but it can not remove blackheads, so this aspect can not be used indiscriminately.