The cost of diffuse large b-cell lymphoma varies depending on the treatment, with the cost of one chemotherapy cycle ranging from $5,000 to $20,000, hematopoietic stem cell transplantation ranging from $100,000 to $400,000, and chimeric antigen receptor T-cell therapy costing about $1.2 million. 1. Chemotherapy for diffuse large b-cell lymphoma incurs different costs due to different drug regimens, the cost of one chemotherapy cycle is around $5,000, the cost of chemotherapy combined with targeted drugs is around $20,000 for one cycle, and the chemotherapy cycles vary according to the drug regimen, usually requiring about 6 cycles. Specific drugs include cyclophosphamide, vinblastine, rituximab and so on. 2. The cost of autologous hematopoietic stem cell transplantation is around 100,000 yuan, and the cost of allogeneic hematopoietic stem cell transplantation is higher, 300,000~400,000 yuan. 3. At present, the most advanced cellular immunotherapy technology in the international arena is chimeric antigen receptor T cell (CART) therapy, which costs about 1.2 million RMB. Diffuse large b-cell lymphoma treatment is different due to different conditions with different medication programs, so the cost is also different, it is recommended to refer to the local charges, specific treatment and medication should be carried out under the guidance of physicians.