Some patients with renal failure uremia may die within months or even days, while some may survive for more than 10 years, or even several 10 years. Therefore, how long uremia can survive, individual variability is very big, first, with the patient found the condition of the early and late relationship, some patients with uremia may be found late, blood creatinine has reached more than 1000 μmoI / L, urea nitrogen has reached more than 50mmol / L, as well as may be combined with severe lethal acidosis, hyperkalemia and heart failure and other serious conditions, the survival time is shorter. The survival time is shorter. Secondly, it may be related to the primary cause of uremia, such as glomerulonephritis caused by uremia, the relative survival time is longer, the prognosis is relatively better. If the uremia is caused by acute glomerulonephritis or ANCA-associated vasculitis or basement membrane nephropathy, the prognosis is relatively poor. Thirdly, it is related to whether the patients with uremia have complications or not, the biggest cause of death in uremia is cardiovascular disease, such as uremia patients with severe malignant arrhythmia, or myocardial infarction and other complications, may have a shorter survival time. Fourthly, it is related to whether the uremic patients have received renal replacement therapy, for example, if the uremic patients do not do renal replacement therapy, such as hemodialysis, peritoneal dialysis, kidney transplantation, etc., the survival time will be shorter. The average survival time of uremia patients who receive renal replacement therapy is 5-10 years.