Lipid-lowering drugs are taken at different times depending on the drug, and are generally divided into nighttime bedtime dosing, daytime dosing, and mixed dosing, as follows: 1. nighttime dosing: statins are recommended to be taken at night before bedtime, and statins act as cholesterol synthesis inhibitors and cholesterol synthesis, mainly during the nighttime sleep state; 2. daytime dosing: ezetimibe is an inhibitor of cholesterol absorption For ezetimibe, it is recommended to take it during the day; 3. Mixed doses: For combined ezetimibe and statins, it is recommended that ezetimibe be taken during the day and statins be taken at night to reduce damage to the liver; patients with mixed hyperlipidemia are recommended to take beta lipid-lowering drugs during the day, mainly for triglyceride reduction, while statins are taken at night mainly for cholesterol reduction, beta Patients with mixed hyperlipidemia are recommended to take beta lipid-lowering drugs during the daytime mainly for triglyceride reduction and statins at night mainly for cholesterol reduction.