Thrush is a common disorder in newborns, usually due to direct and cross-infection. Newborns with thrush experience difficulty nursing, irritability, poor appetite, crying, and mild fever. Treatment of thrush is recommended through both medication and daily care. Medication: For thrush treatment usually involves dissolving one tablet of enzyme-making mycoplasma in cold boiling water or grinding it into a powder and applying it to the area of oral thrush, which is recommended to be applied four to five times a day. Generally, thrush will improve significantly in three to five days through the application of the methotrexate tablets, and if there is no significant effect, a prompt visit to the pediatrician of the hospital is recommended. You can also clean the mouth with a 2% solution of soda water first, and then apply a 1% solution of gentian violet to the mouth with a cotton swab two to three times a day. You can also grind vitamin B and vitamin C into powder, add water and feed. Life care: newborn used bottles, pacifiers, feeding utensils should be cleaned in time, and then it is recommended to steam for ten to 15 minutes. And breastfeeding mothers should wash the areola with warm water before feeding their newborns, and do frequent bathing, change underwear, etc. So it is recommended that newborns with thrush be relieved by both medication and life care.