It is not normal to have a very painful phenomenon after retinoid ointment, which may be an adverse reaction or an allergic reaction to retinoid.
1. Adverse reactions: retinoic acid ointment is indicated for the treatment of acne vulgaris, flat warts, mucous membrane leukoplakia and other diseases. It may cause symptoms of skin irritation such as burning, erythema and flaking, which may make the lesions more visible, but at the same time indicates that the drug is working and is not an exacerbation of the condition. Most of the skin can be adapted and tolerated, the irritation phenomenon can gradually disappear.
2. Allergic reaction: there are some people who have allergic reaction to retinoic acid, erythema, pain, blisters and other symptoms after using retinoic acid ointment. So it is forbidden for those who are allergic to any components of this product.
It is important to note that women within the first 3 months of pregnancy, lactating women. And it should not be used by people with eczema, sunburn, acute and subacute dermatitis. In addition, sharing with soaps, detergents, preparations containing desquamation agents (e.g., peroxybenzoic acid, reserpine, salicylic acid, sulfur), preparations containing ethanol (e.g., after-shave lotion), and isotretinoin can exacerbate skin irritation or drying effects.