Sweating in the middle of the night is generally referred to as night sweats, which refers to abnormal sweating that occurs during sleep, and may be caused by tuberculosis, endocrine diseases, rheumatic immune diseases and so on. 1. Tuberculosis: an infectious disease caused by infection with Mycobacterium tuberculosis, the symptoms of tuberculosis occurring in different parts of the body may be different, but they are generally accompanied by low fever in the afternoon, night sweats (sweating abnormally after going to sleep, and sweating stops after waking up), weight loss and other symptoms. 2. Endocrine diseases: such as menopausal syndrome. Because the disease often has ovarian function decline, hormone level disorders, thus causing changes in the function and metabolism of various organs, so that the autonomic nervous system dysfunction, causing night sweats. 3. Rheumatic immune diseases: such as systemic lupus erythematosus, rheumatic fever, etc., there will also be night sweats and other clinical manifestations. If the situation of sweating in the middle of the night occurs frequently, it is still recommended to go to the hospital in time for the appropriate examination.