If the knee does not hurt when pressed and it hurts when walking, it is considered to be related to osteoarthritis, meniscus injury, chondromalacia patella and other reasons. According to the condition, general treatment, physical therapy, medication, surgery and other methods of treatment can be used. 1. Osteoarthritis: it is caused by degenerative joint disease, patients will have degenerative damage of articular cartilage and osteophytes, which will cause pain when walking. Usually pay attention to rest, avoid overuse of joints. Non-steroidal anti-inflammatory drugs, such as celecoxib, can be applied to treat. It can also be treated with heat therapy and microwave. At the later stage of the disease, artificial joint replacement surgery is feasible. 2. Meniscus injury: meniscus is a meniscus-shaped structure composed of elastic cartilage, which has the function of cushioning pressure, when there is an injury, walking will irritate the meniscus and cause pain. Usually pay attention to rest, you can also apply the loxoprofen sodium treatment, with heat therapy, baking electricity and other treatments. If it is a third-degree injury, there are surgical indications for surgical treatment, such as minimally invasive meniscus suture surgery. 3. Chondromalacia patella: after chronic damage to the patellar cartilage, it will crumble and fall off, causing symptoms such as walking pain and leg weakness. Usually pay attention to rest and avoid overuse of joints. It can be treated with celecoxib and so on. Serious patients can be treated with surgery, such as patellar chondroplasty. It can be seen that the causes of knee pain walking pain is very much including rheumatoid arthritis and cruciate ligament rupture, etc., such as pain is serious, you should go to the hospital in a timely manner to find out the cause of the disease, and then targeted treatment; the above medication needs to be applied under the guidance of a physician.