Some of the patients with urinary protein 3+ can be reduced by eating Wasabi capsule, but most of the patients using Wasabi capsule alone is not particularly good, need to cooperate with other drugs. Wasabi capsule is a kind of traditional Chinese medicine with wasabi flower as the main ingredient, which has the effect of lowering urinary protein to a certain extent. Some patients after the application of urine protein can be changed from 3 + to negative. However, most patients simply applying the effect of reducing urinary protein of Wasabi capsule is not particularly ideal, may need to add other drugs, especially the results of renal puncture pathological type of patients, the simple application of Wasabi capsule effect is often not particularly ideal, may need to add glucocorticoids or other immunosuppressants or even biologics, in order to make the urinary protein to turn negative. The main adverse reaction of this drug is abdominal distension and discomfort, and it is forbidden for pregnant women. Whether or not patients with urinary protein 3+ can simply apply Huangkui capsule treatment, need to have a nephrology clinic doctor, according to the patient’s situation to determine, not self-medication.