It is not accurate to say that post-ovulatory nipple pain is not necessarily a sign of successful pregnancy. Most of the post-ovulatory nipple pain is due to the increase of progesterone in the body, which is a normal physiological reaction, and the nipple pain will gradually ease or even disappear after the onset of menstruation, when women suffer from breast enlargement, breast nodules and other breast diseases caused by a disease. The diagnosis of successful pregnancy is marked by a history of menopause, some women may have early pregnancy reactions such as morning sickness, vomiting or fatigue and weakness, frequent urination and breast tenderness, and the final diagnosis needs to be confirmed by an increase in HCG in the blood and the growth of a gynecological ultrasound cavity with a gestational sac and fetal heartbeat. Therefore, it is inaccurate to diagnose pregnancy only by post-ovulatory nipple swelling, which can easily lead to misdiagnosis.