The patient may be suffering from osteoarthritis in the knee joints, due to the calcium flow in the bones, which will lead to nutritional metabolic disorders in the muscles of the knee joints, resulting in the weakening of the muscles of the legs. 2, it is also possible that the patient is suffering from spinal cervical spondylosis, due to excessive forward flexion of the neck during sleep, which induces an attack of spinal cervical spondylosis. The patient will show a weakening of the muscles of both lower limbs, a feeling of stepping on cotton when walking, and a feeling of chest girdle. Therefore, when the symptoms of weakness and soreness of the legs appear after waking up, the patient should first be instructed to reduce weight-bearing activities, rest in bed, avoid strenuous activities of the neck and waist, and avoid strenuous activities of the joints, and apply topical blood-activating, anti-inflammatory and analgesic drugs to relieve the symptoms. If the symptoms are not relieved within a short period of time, the patient must go to a regular hospital in time to improve the necessary auxiliary examinations, clarify the severity of the disease, and choose a reasonable treatment method.